{"id":12667,"date":"2024-09-16T20:54:14","date_gmt":"2024-09-16T20:54:14","guid":{"rendered":"https:\/\/www.astraformedic.it\/post-transplant-molecular-investigations\/caredx-molecular-testing\/"},"modified":"2025-12-10T23:06:00","modified_gmt":"2025-12-10T23:06:00","slug":"caredx-molecular-testing","status":"publish","type":"page","link":"https:\/\/www.astraformedic.it\/en\/formedic-division\/immunogenetics-and-post-transplant-molecular-investigations\/post-transplant-molecular-investigations\/caredx-molecular-testing\/","title":{"rendered":"CareDx &#8211; Molecular Testing"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"12667\" class=\"elementor elementor-12667 elementor-6686\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a1e810d e-con-full e-flex e-con e-parent\" data-id=\"a1e810d\" data-element_type=\"container\" 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data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;background_motion_fx_motion_fx_scrolling&quot;:&quot;yes&quot;,&quot;background_motion_fx_translateY_effect&quot;:&quot;yes&quot;,&quot;background_motion_fx_blur_effect&quot;:&quot;yes&quot;,&quot;background_motion_fx_blur_level&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:10,&quot;sizes&quot;:[]},&quot;background_motion_fx_blur_range&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:{&quot;start&quot;:0,&quot;end&quot;:100}},&quot;background_motion_fx_translateY_speed&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:7.1,&quot;sizes&quot;:[]},&quot;shape_divider_bottom&quot;:&quot;waves&quot;,&quot;shape_divider_bottom_negative&quot;:&quot;yes&quot;,&quot;background_motion_fx_translateY_affectedRange&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:{&quot;start&quot;:0,&quot;end&quot;:100}},&quot;background_motion_fx_blur_direction&quot;:&quot;out-in&quot;,&quot;background_motion_fx_devices&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;],&quot;_ha_eqh_enable&quot;:false,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t<div class=\"elementor-shape elementor-shape-bottom\" aria-hidden=\"true\" data-negative=\"true\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 1000 100\" preserveAspectRatio=\"none\">\n\t<path class=\"elementor-shape-fill\" d=\"M790.5,93.1c-59.3-5.3-116.8-18-192.6-50c-29.6-12.7-76.9-31-100.5-35.9c-23.6-4.9-52.6-7.8-75.5-5.3\n\tc-10.2,1.1-22.6,1.4-50.1,7.4c-27.2,6.3-58.2,16.6-79.4,24.7c-41.3,15.9-94.9,21.9-134,22.6C72,58.2,0,25.8,0,25.8V100h1000V65.3\n\tc0,0-51.5,19.4-106.2,25.7C839.5,97,814.1,95.2,790.5,93.1z\"\/>\n<\/svg>\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-036b5e0 e-grid e-con-boxed e-con e-child\" data-id=\"036b5e0\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7776094 animated-slow elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"7776094\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;slideInDown&quot;,&quot;_animation_delay&quot;:200,&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Post-transplant molecular testing\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-12d23ba e-flex e-con-boxed e-con e-parent\" data-id=\"12d23ba\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c0bfdca e-flex e-con-boxed e-con e-parent\" data-id=\"c0bfdca\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6374081 elementor-widget elementor-widget-elementskit-tab\" data-id=\"6374081\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"elementskit-tab.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"ekit-wid-con\" >        <div class=\"elementkit-tab-wraper   elementskit-fitcontent-tab \">\n            <ul class=\"nav nav-tabs elementkit-tab-nav \">\n                                    <li class=\"elementkit-nav-item elementor-repeater-item-6342332\">\n                        <a class=\"elementkit-nav-link  active left-pos \" id=\"content-63423326ade85519705f-tab\" data-ekit-handler-id=\"tab-6342332\" data-ekit-toggle=\"tab\" data-target=\"#content-63423326ade85519705f\" data-ekit-toggle-trigger=\"click\" aria-describedby=\"content-63423326ade85519705f\" href=\"#content-63423326ade85519705f\">\n                            <div class=\"ekit-icon-image elementskit-tab-icon\"><img decoding=\"async\" width=\"199\" height=\"86\" src=\"https:\/\/www.astraformedic.it\/wp-content\/uploads\/2024\/06\/cropped-header-logo-caredx-2-e1717410709714.png\" class=\"attachment-full size-full\" alt=\"\" draggable=\"false\" \/><\/div>                            <div class=\"ekit-tab-title-group\">\n                                                                <span class=\"elementskit-tab-title\"><\/span>\n                            <\/div>\n                        <\/a>\n                    <\/li>\n                                <\/ul>\n\n\t\t\t<div class=\"tab-content elementkit-tab-content\">\n\t\t\t\t\t\t\t\t\t<div class=\"tab-pane elementkit-tab-pane elementor-repeater-item-6342332  active show \" id=\"content-63423326ade85519705f\" role=\"tabpanel\" aria-labelledby=\"content-63423326ade85519705f-tab\">\n\t\t\t\t\t\t<div class=\"animated fadeIn\">\n\t\t\t\t\t\t\t\n\t\t<div class=\"widgetarea_warper widgetarea_warper_editable\" data-elementskit-widgetarea-key=\"6374081\"  data-elementskit-widgetarea-index=\"6342332\">\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t\t<div class=\"ekit-widget-area-container\">\n\t\t\t\t\t\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"6145\" class=\"elementor elementor-6145\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"elementskit_content\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7b5aad e-flex e-con-boxed e-con e-parent\" data-id=\"c7b5aad\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f4c4cb0 elementor-widget elementor-widget-text-editor\" data-id=\"f4c4cb0\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"p1\"><b>Dedicato ai pazienti trapiantati. Leader nell\u2019innovazione.<\/b><\/p><p class=\"p2\"><span class=\"s1\"><b>Cura personalizzata per ogni fase del percorso del trapianto.<\/b><\/span><\/p><p class=\"p3\">Siamo impegnati e determinati a migliorare le analisi per i pazienti trapiantati, offrendo soluzioni innovative e avanzate lungo tutto il percorso del paziente. La nostra realt\u00e0 si fonda su cinque valori fondamentali che caratterizzano tutto il nostro operato: innovazione, centralit\u00e0 del paziente, responsabilit\u00e0, miglioramento continuo e una cultura basata sulla collaborazione e su un atteggiamento propositivo. Questi valori sono il motore che guida ogni nostra azione.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n        <\/div>\n    <\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-93bed62 e-flex e-con-boxed e-con e-parent\" data-id=\"93bed62\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false,&quot;ekit_has_onepagescroll_dot&quot;:&quot;yes&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e474cd2 elementor-widget elementor-widget-elementskit-accordion\" data-id=\"e474cd2\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;ekit_we_effect_on&quot;:&quot;none&quot;}\" data-widget_type=\"elementskit-accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"ekit-wid-con\" >\n        <div class=\"elementskit-accordion accoedion-primary\" id=\"accordion-6ade7315c24f1\">\n\n            \n                <div class=\"elementskit-card \">\n                    <div class=\"elementskit-card-header\" id=\"primaryHeading-0-e474cd2\" role=\"heading\" aria-level=\"3\">\n                        <a href=\"#collapse-7c965876ade7315c24f1\" class=\"ekit-accordion--toggler elementskit-btn-link collapsed\" role=\"button\" data-ekit-toggle=\"collapse\" data-target=\"#Collapse-7c965876ade7315c24f1\" aria-expanded=\"false\" aria-controls=\"Collapse-7c965876ade7315c24f1\">\n                            \n                            <span class=\"ekit-accordion-title\">AlloSeq HCT<\/span>\n\n                            \n                                <div class=\"ekit_accordion_icon_group\">\n                                    <div class=\"ekit_accordion_normal_icon\">\n                                        <!-- Normal Icon -->\n\t\t\t\t\t\t\t\t\t\t<i class=\"icon icon-down-arrow1\"><\/i>                                    <\/div>\n\n                                    <div class=\"ekit_accordion_active_icon\">\n                                        <!-- Active Icon -->\n\t\t\t\t\t\t\t\t\t\t<i class=\"icon icon-up-arrow\"><\/i>                                    <\/div>\n                                <\/div>\n\n                            \n                                                    <\/a>\n                    <\/div>\n\n                    <div id=\"Collapse-7c965876ade7315c24f1\" class=\" collapse\" role=\"region\" aria-labelledby=\"primaryHeading-0-e474cd2\" data-parent=\"#accordion-6ade7315c24f1\">\n\n                        <div class=\"elementskit-card-body ekit-accordion--content\">\n                            <p class=\"p1\"><strong>AlloSeq HCT Innovation in<\/strong> <strong>chimerism<\/strong> monitoring<\/p>\n<p class=\"p1\">The latest innovation in chimerism testing offers optimized workflow with best-in-class sensitivity<br \/>. Changes in chimerism after hematopoietic cell transplantation can be<br \/>an early indication of relapse. Key Features:<br \/>- An NGS-based chimerism testing solution capable of determining the relative contribution<br \/>of up to 3 genomes in a single sample, meaning up to two donors for each recipient<br \/>- A kit-based test delivering high-quality data with a recommended input of 10 ng gDNA and<br \/>up to 96 samples per batch<br \/>- One-step multiplex test using 202 SNPs across all autosomal chromosomes to differentiate between<br \/>recipient and donor(s) gDNA.<br \/>- A highly sensitive test<\/p>\n                        <\/div>\n\n                    <\/div>\n\n                <\/div><!-- .elementskit-card END -->\n\n                \n                <div class=\"elementskit-card \">\n                    <div class=\"elementskit-card-header\" id=\"primaryHeading-1-e474cd2\" role=\"heading\" aria-level=\"3\">\n                        <a href=\"#collapse-1d2b63b6ade7315c24f1\" class=\"ekit-accordion--toggler elementskit-btn-link collapsed\" role=\"button\" data-ekit-toggle=\"collapse\" data-target=\"#Collapse-1d2b63b6ade7315c24f1\" aria-expanded=\"false\" aria-controls=\"Collapse-1d2b63b6ade7315c24f1\">\n                            \n                            <span class=\"ekit-accordion-title\">AlloSeq cfDNA<\/span>\n\n                            \n                                <div class=\"ekit_accordion_icon_group\">\n                                    <div class=\"ekit_accordion_normal_icon\">\n                                        <!-- Normal Icon -->\n\t\t\t\t\t\t\t\t\t\t<i class=\"icon icon-down-arrow1\"><\/i>                                    <\/div>\n\n                                    <div class=\"ekit_accordion_active_icon\">\n                                        <!-- Active Icon -->\n\t\t\t\t\t\t\t\t\t\t<i class=\"icon icon-up-arrow\"><\/i>                                    <\/div>\n                                <\/div>\n\n                            \n                                                    <\/a>\n                    <\/div>\n\n                    <div id=\"Collapse-1d2b63b6ade7315c24f1\" class=\" collapse\" role=\"region\" aria-labelledby=\"primaryHeading-1-e474cd2\" data-parent=\"#accordion-6ade7315c24f1\">\n\n                        <div class=\"elementskit-card-body ekit-accordion--content\">\n                            <p class=\"p1\"><b>Donor-derived cell-free DNA test for organ transplant monitoring.<\/b><\/p>\n<p class=\"p2\"><span class=\"s1\">Determination of the level of <\/span><span class=\"s2\">Circulating Cell-Free<\/span><span class=\"s1\"> DNA derived from the donor in transplant recipients. The relative quantification of the level of <\/span><span class=\"s2\">Circulating Cell-Free<\/span><span class=\"s1\"> DNA derived from the donor can help improve transplant surveillance. <\/span><span class=\"s2\">Circulating Cell-Free DNA is fragmented DNA in the bloodstream that comes from cells undergoing injury and dying.<\/span><span class=\"s1\"> When transplant injury occurs, the <\/span><span class=\"s2\">Circulating Cell-Free<\/span><span class=\"s1\"> DNA derived from the donor (dd-cfDNA) increases in the blood. AlloSeq cfDNA measures the <\/span><span class=\"s2\">Circulating Cell-Free<\/span><span class=\"s1\"> DNA derived from the donor (dd-cfDNA) using low DNA input, next-generation sequencing (NGS) technology<\/span> <span class=\"s1\"> and optimized analysis to improve transplant surveillance.<\/span><\/p>\n<p class=\"p4\">Revolutionizing Chimerism Monitoring<\/p>\n<p class=\"p4\">The latest innovation in chimerism testing offers streamlined workflow with best-in-class sensitivity.<\/p>\n<p class=\"p4\">Chimerism changes after hematopoietic cell transplant can be an early indication of relapse.*<\/p>\n<p class=\"p3\">\n<p class=\"p4\">Key Features:<\/p>\n<ul class=\"ul1\">\n<li class=\"li5\"><span class=\"s4\">A NGS-based chimerism testing solution that is able to determine the relative contribution of up to 3 genomes in a single sample, i.e., up to two donors per recipient <\/span><\/li>\n<li class=\"li5\"><span class=\"s4\">A kit-based test that offers high-quality data with a recommended input of 10 ng of gDNA and up to 96 samples per batch <\/span><\/li>\n<li class=\"li5\"><span class=\"s4\">- One-step multiplex assay that utilizes 202 SNPs across all autosomal chromosomes to differentiate between recipient and donor(s) gDNA <\/span><\/li>\n<\/ul>\n<p class=\"p4\">-<span class=\"Apple-converted-space\"> <\/span>A highly sensitive, scalable assay with time-saving automated analysis software<\/p>\n                        <\/div>\n\n                    <\/div>\n\n                <\/div><!-- .elementskit-card END -->\n\n                                        <\/div>\n    <\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Post-transplant molecular testing Edit Content Dedicato ai pazienti trapiantati. Leader nell\u2019innovazione. Cura personalizzata per ogni fase del percorso del trapianto. Siamo impegnati e determinati a migliorare le analisi per i pazienti trapiantati, offrendo soluzioni innovative e avanzate lungo tutto il percorso del paziente. La nostra realt\u00e0 si fonda su cinque valori fondamentali che caratterizzano tutto [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":12453,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":"","_members_access_role":[],"_members_access_error":""},"class_list":["post-12667","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>CareDx - Molecular Testing - AstraFormedic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.astraformedic.it\/en\/formedic-division\/immunogenetics-and-post-transplant-molecular-investigations\/post-transplant-molecular-investigations\/caredx-molecular-testing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CareDx - Molecular Testing - AstraFormedic\" \/>\n<meta property=\"og:description\" content=\"Post-transplant molecular testing Edit Content Dedicato ai pazienti trapiantati. 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